The Myth of Equipoise in Phase 1 Clinical Trials

Steve Simon

2008-11-05

Interesting quote: The statistician who supposes that his main contribution to the planning of an experiment will involve statistical theory, finds repeatedly that he makes his most valuable contribution simply by persuading the investigator to explain why he wishes to do the experiment, by persuading him to justify the experimental treatments, and to explain why it is that the experiment, when completed, will assist him in his research. – Gertrude M. Cox. (I can’t recall the original source where I found this quote. Sorry!)

You can find an earlier version of this page on my original website.