This page promotes a new approach to a broad class of models (spatio-temporal models

- latent variable models
- mixed models) using a fast approximation to the Bayesian solution. It runs under R and appears to handle very large datasets. I have not had a chance to try this
- but it looks very interesting.

Havard Rue. Bayesian computing with INLA. Available at http://www.r-inla.org/home.