If you want to understand the value of genomic medicine, you can learn a lot by reviewing the case of Nicholas Volker, one of the first success stories in this area. Here’s a nice review.
Sarah DeWeerdt. Genetics: Clues in the code. Nature 540, S104–S105, (22 December 2016). doi:10.1038/540S104a. Available in html format.
You can find an earlier version of this page on my blog.