If you want to understand the value of genomic medicine, you can learn a lot by reviewing the case of Nicholas Volker, one of the first success stories in this area. Here’s a nice review.
Sarah DeWeerdt. Genetics: Clues in the code. Nature 540, S104–S105, (22 December 2016). doi:10.1038/540S104a. Available at http://www.nature.com/nature/journal/v540/n7634_supp/full/540S104a.html.